ABSTRACT
Physicians of different specialties accumulate the clinical material about the atypical course of different diseases during the pandem-ics of the new coronavirus infection (COVID-19). Mucormycosis is one of such diseases, which was earlier observed in immunocom-promised patients with the uncontrollable diabetes mellitus, transplant recipients, patients with hematological diseases, neoplasias (especially after chemotherapy), or the HIV-infection. Aim of the study. Advancing the treatment tactics in patients with necrotic fungal rhinoorbital lesions in the COVID-19 infection based on the analysis of clinical and pathomorphological disease features. Material and methods. A prospective analysis of 13 clinical cases was conducted along with the pathomorphological study of the biopsy material. Results. Vascular and perineural changes were detected in affected tissues, which may confirm the specific pathogenesis of fungal lesions of the rhinofacial region in the post-COVID syndrome. © 2023, Media Sphera Publishing Group. All rights reserved.